Tofranil Information

Basic information about Tofranil (Imipramine)

Tofranil (Imipramine) is widely used for treating depression.

As an tricyclic antidepressant Tofranil (Imipramine) acts by increasing the activity of certain chemicals in the brain that help elevate mood.

It is better to store Tofranil (Imipramine) at temperature of 20-30 degrees C (e.g. 35-85 F). It is adviced to store Imipramine far from moisture and heat, and out of children’s and pet’s reach.

If you have any questions about using Tofranil (Imipramine), please ask your doctor. Also you can ask our support - Ask Question

If think that you overdose Tofranil (Imipramine) call your healthcare professional immediately

Warnings and Precautions about Tofranil (Imipramine)

If you have a history of serious diseases, you need to consult your healthcare professional prior to intake of Tofranil (Imipramine).

Every patient should understand that nearly all remedy might cause side effects if it is taken by wrong schedule, or you have ever had allergic reaction to it.

However, most people do not suffer from any side effects. Tofranil (Imipramine) is a safe and effective medication that is used for treatment of depression.

The most common side effects are:

Check with your doctor if any of these most common side effects persist or become bothersome:

• excitement, weight loss or gain, headache, drowsiness, nausea, weakness, pupil dilation, upset stomach, dizziness, sweating, vomiting, dry mouth, tiredness, impotence, nightmares, sensitivity to sunlight.

Seek medical attention right away if any of these severe side effects occur:

• worsening of depression, blurred vision or other vision changes, twitching of the face or tongue, ringing in the ears, trouble sleeping, impulsive behavior or other unusual changes in behavior, changes in sex drive, uncontrolled movements of arms and legs or stiffness, frequent or difficult urination, fast slow or irregular heartbeat, suicidal thinking or behavior, fever, chest pain, severe dizziness or drowsiness, tremor, yellowing of the skin or eyes, stomach pain, sore throat, trouble walking or keeping your balance, confusion, seizures, mental or mood changes (irritability; eg; mood swings; agitation; restlessness; nervousness; increased anxiety.) , fainting, unusual bleeding or bruising, panic attacks, constipation, jaw neck or muscle spasms, severe allergic reactions (difficulty breathing, swelling of the mouth face lips or tongue, itching, hives, rash, tightness in the chest.) , swelling of the testicles, hallucinations.

Do not use Tofranil if:

• you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the last 14 days, or if you are taking astemizole, droperidol, or terfenadine.
• you are allergic to any ingredient in Tofranil;
• you are recovering from a recent heart attack.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Tofranil . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you have a history of suicidal thoughts or behavior, bipolar disorder, or any other mental disorders; you are undergoing electroshock therapy; or you are scheduled to have any surgery.
• if you have allergies to medicines, foods, or other substances
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you drink alcohol-containing beverages daily or you have a history of alcohol abuse
• if you take thyroid medicine or you have a history of overactive thyroid, glaucoma, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

Some MEDICINES MAY INTERACT with Tofranil . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Clonidine, guanethidine, or guanfacine because their effectiveness may be decreased by Tofranil
• Barbiturates (eg, phenobarbital) or phenytoin because they may decrease Tofranil 's effectiveness
• Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) because the risk of their side effects may be increased by Tofranil
• Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol because the risk of high blood pressure, serious heart problems (eg, irregular heartbeat), or seizures may be increased
• Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine because they may increase the risk of Tofranil 's side effects

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