Emsam Information

Basic information about Emsam (Selegiline)

Emsam (Selegiline) is indicated to cure depression.

As an monoamine oxidase inhibitor (MAOI) Selegiline works by balancing serotonin in brain.

It is better to store Emsam (Selegiline) between 20 and 30 degrees C. It is recommended to store Emsam away from moisture and heat, and in a safe place, far from reach of children.

If you are unsure about taking Emsam (Selegiline), feel free to attend your healthcare provider. You may also ask our support - Ask Question

If think that you overdose this medicine call emergency as soon as you can

Warnings and Precautions about Emsam (Selegiline)

If you have any medical conditions or serious diseases, you may prefer to visit your pharmacist before taking Emsam (Selegiline).

You should pay attention that every drug is able to lead to side effects if it is taken by wrong schedule, or you have allergic reaction to it.

However, most patients do not suffer from any side effects. Emsam (Selegiline) is a safe and effective medication that is used to improve condition of patients suffering from depression.

The most common by-effects are:

Check with your doctor if any of these most common side effects persist or become bothersome:

• sleeplessness, dizziness, dry mouth, diarrhea.

Seek medical attention right away if any of these severe side effects occur:

• chest pain, new or worsening agitation aggressiveness anxiety exaggerated feeling of well-being hostility impulsiveness inability to sit still irritability panic attacks or sleeplessness, abnormal thinking, increased sweating, enlarged pupils, fast slow or irregular heartbeat, nausea, swelling of the arms or legs, painful menstruation, severe headache, memory loss, vomiting, neck stiffness or soreness, sensitivity to light, severe allergic reactions (swelling of the mouth face lips or tongue, difficulty breathing, hives, rash, itching, tightness in the chest.) , changes in sexual ability or desire.

Do not use Emsam if:

• you will be undergoing elective surgery with general anesthesia or will be receiving cocaine or local anesthesia containing sympathomimetic vasoconstrictors;
• you are taking another MAOI (e.g., phenelzine), a sympathomimetic, including an amphetamine, a cold product, or certain diet pills or preparations (e.g., ephedrine, phenylephrine, phenylpropanolamine, pseudoephedrine), or sibutramine, or if you have taken any of these medicines within the past 7 days;
• you are taking a 5-HT agonist (e.g., sumatriptan), apraclonidine, carbamazepine, methylphenidate, oxcarbazepine, or nefazodone;
• you are taking bupropion, buspirone, cyclobenzaprine, dextromethorphan, meperidine, methadone, a norepinephrine reuptake inhibitor (e.g., atomoxetine), propoxyphene, a selective serotonin reuptake inhibitor (SSRI) (e.g., paroxetine), a serotonin and norepinephrine reuptake inhibitor (e.g., duloxetine, venlafaxine), St. John's wort, a tetracyclic antidepressant (e.g., mirtazapine), tramadol, or a tricyclic antidepressant (e.g., amitriptyline), or if you have taken any of these medicines within the past 7 days;
• you are allergic to any ingredient in Emsam;
• you are taking fluoxetine or have taken it within the past 5 weeks;
• you have certain adrenal gland problems (eg, pheochromocytoma).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Emsam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you have allergies to medicines, foods, or other substances
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have a history of ulcer, heart problems, recent heart attack, seizures, blood problems, or a metabolism disorder
• if you have a history of bipolar disorder, mania, mood or mental problems, suicidal thoughts or attempts, or uncontrolled muscle movements (eg, twitching of the face and tongue and involuntary movements of the arms and legs)
• if you are pregnant, planning to become pregnant, or are breast-feeding

Some MEDICINES MAY INTERACT with Emsam. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Nefazodone or tryptophan because nausea, dizziness, mental or mood changes, seizures, fever, or breathing or heart problems may occur
• Tramadol because the risk of seizures may be increased
• Carbamazepine or oxcarbazepine because they may increase the risk of Emsam's side effects 5-HT1 agonists (eg, sumatriptan), insulin, a meglitinide antidiabetic (eg, nateglinide), methylphenidate, or a sulfonylurea (eg, glipizide) because the risk of their side effects may be increased by Emsam
• Bupropion, cyclobenzaprine, dextromethorphan, a MAOI (eg, phenelzine), meperidine, methadone, a norepinephrine reuptake inhibitor (eg, atomoxetine), oral selegiline, propoxyphene, a serotonin or norepinephrine reuptake inhibitor (eg, duloxetine, venlafaxine), sibutramine, a SSRI (eg, fluoxetine), St. John's wort, sympathomimetics (eg, amphetamine , ephedrine, phenylephrine, phenylpropanolamine, pseudoephedrine), a tetracyclic antidepressant (eg, mirtazapine), or a tricyclic antidepressant (eg, amitriptyline) because serotonin syndrome (eg, fever, muscle stiffness or rigidity, vital sign changes, mental or mood changes, coma) may occur
• Apraclonidine or buspirone because severe high blood pressure may occur

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